Fractional Chief Medical Officer

tranScrip’s Fractional CMO service gives biotech companies immediate access to flexible, senior, industry-experienced medical leadership, tailored to the stage of development and therapeutic need.


Unlike traditional CROs or standalone consultants, tranScrip combines strategic CMO-level oversight with the full depth of its multidisciplinary teams in regulatory, nonclinical, CMC, clinical operational, drug safety, commercial and translational science.

This means companies don’t just get a single expert, but a connected bespoke network – as needed – that can anticipate risks, shape development strategy, and execute solutions seamlessly. The result is flexible, informed leadership, faster decision-making, and the assurance that every critical step is guided by people who have done it before.

Fractional CMO

What a tranScrip CMO provides

●  Strategic medical leadership across all stages of development
●  Access to a network of other key SME personnel
●  Oversight of product strategy, cross-functional and clinical development plans
●  Detailed study design(s) through to full protocol development and delivery
●  Representation in interactions with global health authorities
●  Leadership of medical affairs strategy and plans
●  Consulting with broader stakeholders and prospective investors / partners
●  Strategic development insight for out-licensing options

Why choose a tranScrip CMO

Exceptional Seniority and Credibility

Every tranScrip Fractional CMO is an industry-tested pharmaceutical physician with a track record of guiding programmes through complex development paths.

The Power of a Whole Team, Not One Individual

Your Fractional CMO is backed by tranScrip’s full team of regulatory, nonclinical, clinical operational, commercial and translational experts. This collective strength means you get rapid, authoritative answers across disciplines — not the limits of a single consultant who may be unavailable when you need them most.

Flexible Leadership, Precisely When You Need It

Whether for a critical milestone, investor engagement, programme rescue, or sustained oversight, tranScrip provides senior medical leadership on a fractional, scalable basis — without the cost or commitment of a permanent CMO.

A True Partner in Value Creation

We work as an extension of your team, bringing clarity, confidence, and strategic alignment to maximise the value of your product — and the long-term success of your company.

“We partnered with tranScrip to provide us with a Fractional Chief Medical Officer (CMO), and the strategic impact was immediately apparent. Their physician, Board certified in clinical pharmacology, integrated seamlessly into our early development team, providing the translational medicine leadership required at a key stage of our programme. From forging a robust, defensible early clinical development plan, including a first-in human protocol synopsis with biostats inputs and power calculations, to helping shape the translational biomarker strategy, their extensive clinical track record, coupled with a flexible resourcing model, brought tangible progress to a first-in-class programme for a novel indication with little or no clinical precedents.”

Founder and CEO

Emerging Biotech

Case Study

CMO for a Novel Early-Phase Development Programme

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Article

Unlocking Value with a Fractional Chief Medical Officer

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Explore further

Don’t let gaps in medical leadership slow your progress. Speak with us now to see how tranScrip’s Fractional CMO can help drive momentum, transform your journey — from TRANslation to preSCRIPtion.

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